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The enzyme that gives a powerful tool known as a “base editor” the ability to change DNA also has an off-target effect on RNA (above). NOBEASTSOFIERCE SCIENCE/ALAMY STOCK PHOTO

Powerful CRISPR cousin accidentally mutates RNA while editing DNA target

When researchers first reported 3 years ago that they had created base editors, a version of the powerful genome-editing tool CRISPR, excitement swirled around their distinct powers…

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Health workers at an Ebola treatment center in the Democratic Republic of the Congo, which was attacked earlier this year by armed men JOHN WESSELS/AFP/GETTY IMAGES

Ebola outbreak in Congo still not an international crisis, WHO decides

No need to sound the world’s loudest public health alarm bell about the lingering Ebola outbreak in the Democratic Republic of the Congo (DRC), an…

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A researcher adjusts a microplate containing embryos undergoing gene editing with CRISPR. An expert panel has recommended that all such experiments be submitted to a global registry.   MARK SCHIEFELBEIN/AP PHOTO

WHO panel proposes new global registry for all CRISPR human experiments

There’s an “urgent need” to create a transparent global registry that would list all experiments related to human genome editing, an expert committee convened to…

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HIV integrates its genome (yellow) into human chromosomes, and cells that indirectly copy that genome as they replicate may complicate cure efforts.   DAVID S. GOODSELL/HIVE CENTER

Curing HIV just got more complicated. Can CRISPR help?

SEATTLE, WASHINGTON—Antiretroviral (ARV) drugs have turned HIV infection from a death sentence to a chronic condition. In most people the drugs routinely tamp HIV levels…

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Conducting research that alters human embryos with the genome editor CRISPR (shown here) would not be banned if a proposed moratorium goes in place, but implanting altered human embryos would.   MARK SCHIEFELBEIN/AP PHOTO

New call to ban gene-edited babies divides biologists

   A prominent group of 18 scientists and bioethicists from seven countries has called for a global “moratorium” on introducing heritable changes into human sperm,…

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