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Category: Science (features)

Rudolf Jaenisch made the first transgenic mouse in 1974 and has pioneered the engineering of CRISPR mice. Photo: Ken Richardson

Mice Made Easy

In the beginning of 2013, Michael Wiles sat down with high-level managers of the Jackson Laboratory in Bar Harbor, Maine, and told them about a…

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Bongekile Sokhela consults with Dr. Richard Lessells at Hlabisa Provincial Hospital in the KwaZulu-Natal province of South Africa. Sokhela has both HIV and tuberculosis — a brutal, one-two punch that’s exacerbating epidemics of both diseases in South Africa. Photo by William Brangham/PBS NewsHour

South Africa’s bid to end AIDS

On a Wednesday morning in April, a line of 600 HIV-infected people snakes through the hallways to the first waiting room of the Themba Lethu…

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Means to an End

After what Shane Ryan calls “a silly, stupid weekend” in late April, he joined the many other men in San Francisco, California, who line up…

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No End in Sight

On 6 December 2013, Pedro Robles spent 14 hours in an ambulance being driven up Mexico’s Baja California Peninsula. The 51-year-old man was not rushed…

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Resistance is futile. A 3D map from cryoelectron tomography of a "trimeric spike" of HIV's gp120 (red) bound by a potent bNAb (blue). CREDIT: FROM THE WORK OF SRIRAM SUBRAMANIAM AND COLLEAGUES/NIH

Bound for Glory

  The discovery of antibodies that foil almost every HIV variant has transformed the AIDS vaccine search. In 2006, the International AIDS Vaccine Initiative (IAVI)…

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