HIV integrates its genome (yellow) into human chromosomes, and cells that indirectly copy that genome as they replicate may complicate cure efforts. DAVID S. GOODSELL/HIVE CENTER
SEATTLE, WASHINGTON—Antiretroviral (ARV) drugs have turned HIV infection from a death sentence to a chronic condition. In most people the drugs routinely tamp HIV levels…
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Conducting research that alters human embryos with the genome editor CRISPR (shown here) would not be banned if a proposed moratorium goes in place, but implanting altered human embryos would. MARK SCHIEFELBEIN/AP PHOTO
A prominent group of 18 scientists and bioethicists from seven countries has called for a global “moratorium” on introducing heritable changes into human sperm,…
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Community health workers with the Population Effects of Antiretroviral Therapy to Reduce HIV Transmission study did door-to-door HIV testing of 1 million people annually for 3 years. KIM CLOETE
SEATTLE, WASHINGTON—The recipe for ending HIV epidemics seems straightforward. Introduce widespread testing. Immediately put those who test positive on antiretroviral (ARV) drugs, which suppress the…
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Syngenta researcher Shujie Dong isolates corn embryos to genome edit them with CRISPR. J. COHEN/SCIENCE
The genome editor CRISPR has transformed many areas of biology, but using this tool to enhance certain varieties of crops such as wheat and corn…
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This rice has had some of its DNA bases altered by a form of the genome editor CRISPR, but some of them were not the intended targets. JON COHEN
Variations of the genome editor CRISPR have wowed biology labs around the world over the past few years because they can precisely change single DNA…
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President Donald Trump announced an initiative to end HIV/AIDS in the United States during his State of the Union address. DOUG MILLS/PICTURE-ALLIANCE/DPA/AP IMAGES
The people who planted the seed that led President Donald Trump to announce a new agenda to end AIDS in his State of the Union…
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A policeman in Karachi, Pakistan, protects a health worker as she administers a polio vaccine. ASIF HASSAN/AFP/GETTY IMAGES
In 2003, epidemiologist Nicholas Thomson was doing HIV prevention work in Chiang Mai, Thailand, when the country’s president, Thaksin Shinawatra, launched an aggressive war on…
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Michel Sidibé DENIS BALIBOUSE/REUTERS
A board that oversees the Joint United Nations Programme on HIV/AIDS (UNAIDS) in Geneva, Switzerland, the global command center in the fight against the infectious…
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Researchers at Oregon Health & Science University in Portland used the genome editor CRISPR to correct a mutation that causes a heart problem. The embryos were not implanted. OHSU
The world urgently needs better international oversight of “genome editing in human embryos for reproductive purposes,” says an editorial co-written by the heads of the…
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