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The genome editor CRISPR cuts DNA with help from a guide RNA (green and red) and a Cas9 enzyme (outline) that latches onto a three-base sequence (yellow). KC ROEYER/UNIVERSITY OF CALIFORNIA, BERKELEY

Upgrade makes genome editor CRISPR more muscular, precise

You wouldn’t know it from the excitement generated by the revolutionary genome editing method known as CRISPR, but as practiced now, it is far from…

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Protesters from several health advocacy groups gathered this morning in front of the Washington, D.C., offices of the Centers for Disease Control and Prevention. Alex Morash/The National LGBTQ Task Force

CDC word ban? The fight over seven health-related words in the president’s next budget

Presidential budget requests are political documents, and the wrong word can send a confusing message—and trigger controversy. President Donald Trump’s administration appears to have kicked…

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Lab technician and Ebola survivor Sukato Mandzomba (front) worked with Peter Piot (back) in 1976 and again in 2016.

Forty years later, Ebola survivors are still making antibodies to the lethal virus

Forty years after the first documented Ebola outbreak, some of the survivors still have antibodies against the virus, a new study reveals. The find bolsters…

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Teens play foosball at a youth center run by the Desmond Tutu HIV Foundation near Cape Town, South Africa. A new report says HIV/AIDS prevention and treatment programs often fail to reach boys. Photo: Jason Kane/PBS NewsHour

For World AIDS Day, an urgent call for more attention to men and boys

Friday is World AIDS Day, and pronouncements once again are making proud declarations of the many strides made against HIV in the past year. But…

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Eva Harris (far right) has led a dengue study in Nicaragua that for more than 12 years has regularly taken blood samples from children. Alejandro Belli/PLOS Pathogens

New evidence that dengue antibodies trigger life-threatening infections

It’s a disease theory fit for a spy novel: Protective antibodies can turn double agent, teaming up with the dengue virus to make an infection…

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Variations of the CRISPR DNA editor can change one DNA base into another. Shaury Nash/Flickr (CC BY SA 2.0)

Novel CRISPR-derived ‘base editors’ surgically alter DNA or RNA, offering new ways to fix mutations

Since the start of the CRISPR craze 5 years ago, scientists have raced to invent ever-more-versatile or efficient variations of this powerful tool, which vastly…

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